discusses a series of compounds that were synthesised and tested for activity against the opioid receptors.
Expect to see these compounds in a cut near you! There's no excuse not to expect more from your high.
For an insight into the increasing sophistication of the techniques around those supplying drugs of abuse consider, World-wide cocaine cut mystery: from Mindhacks where the authors says,
"The fact that this relatively obscure compound [levamisole] has become so common in the global cocaine industry might suggest that it was selected on the basis of its pharmacological properties.
In other words, on the basis of the study of neuroscience. One study reported that professional heroin cutters can charge up to $20,000 a kilo and I wouldn't be surprised whether the big players in the cocaine industry can afford to pay for neuroscientists or pharmacologists to tweak their products."